Lab News

To trim away a protein

Laboratory Journal - 3 hours 18 min ago
In our body, proteins carry out almost all essential processes, and protein malfunction causes many diseases. To study the function of a protein, researchers remove it from the cell and subsequently analyze the consequences. The two methods typically used are genome editing by CRISPR/Cas, and RNA interference, acting on the level of DNA or RNA, respectively. However, their influence on protein amounts is indirect and takes time. Scientists now present a new method, called Trim-Away, allowing to directly and quickly deplete any protein from any cell type.
Categories: Life Science News

Re-Scan Confocal Microscopy

Bio Imaging - 3 hours 41 min ago
As we all know, the most important property of the confocal microscope is optical sectioning (axial resolution). A bit forgotten fact is that confocal microscopy has the potential of lateral super-resolution (better resolution than Abbe’s Law dictates). This lateral super-resolution can only be obtained by sacrificing precious fluorescence signal and thus by getting noisy images. This problem has now been solved by a simple re-design of the optics: Re-scan Confocal Microscopy (RCM). Why Confocal Microscopes Should Give Super-Resolution
Categories: Life Science News

Changeover made easy: Replace your old photometer with a new photoLab 7600 UV-VIS

Laboratory Journal - 3 hours 41 min ago
Save 1000,- € on purchase of a photoLab 7600 UV-VIS UV-VIS Spectral photometer by replacing an old photometer (invoice/declaration of ownership required).  Here is a link to the special offer.
Categories: Life Science News

Biomedical Imaging: Quantum Dots Mark the Spot

Bio Imaging - 6 hours 3 min ago
A simple way to harness the incredible brightness of quantum dots—tiny fluorescent semiconductor crystals—and realize highly sensitive molecular imaging of cancer cells and other biomedical targets has been developed by researchers at Riken.
Categories: Life Science News

Protein 'intentionally' terminates own synthesis by destabilizing synthesis machinery -- the ribosome

Life Science News - 20 November 2017 - 4:13pm
Cell biologists have discovered that a protein, during its synthesis, may destabilize the structure of the ribosome and end its own synthesis prematurely, and found that this phenomenon is used for adapting the cell to its environment.
Categories: Life Science News

This material does weird things under pressure

Science News - 20 November 2017 - 3:00pm
A new metamaterial has a seemingly impossible property: It swells when squeezed.
Categories: Life Science News

What's in your wheat? Scientists piece together genome of most common bread wheat

Life Science News - 20 November 2017 - 2:54pm
Scientists have successfully used two separate gene technologies to assemble the most complete genome sequence to date of Triticum aestivum, the most common cultivated species of wheat used to make bread.
Categories: Life Science News

Watch NASA’s mesmerizing new visualization of the 2017 hurricane season

Science News - 20 November 2017 - 1:00pm
Swirls of sand, sea salt and smoke make atmospheric currents visible in a new NASA visualization.
Categories: Life Science News

Ultrasound Bioprobe: Viewing Sub-Cellular Structures at Nanoscale Resolution

Bio Imaging - 20 November 2017 - 11:38am
To undergo high-resolution imaging, cells often must be sliced and diced, dehydrated, painted with toxic stains, or embedded in resin. For cells, the result is certain death. But if researchers can only view the inner workings of dead cells, they’re only seeing part of the story. They cannot monitor living cells’ dynamic real-time processes, such as metabolic reactions or responses to diseases or treatments.
Categories: Life Science News

Altering Hydrophobin Film with Ethanol

Bio Imaging - 20 November 2017 - 9:23am
Hydrophobins are fungal proteins with many potential applications due to their ability to self-assemble into amphipathic films at hydrophobic:hydrophillic interfaces. The ability to manipulate surface characteristics of hydrophobin films is highly desirable. Here, we have shown that by adjusting the amount of ethanol in an aqueous solution containing the hydrophobin EASΔ15, protein films with distinct features and properties can be obtained, as confirmed by AFM and contact angle measurements. Introduction to Hydrophobin Proteins
Categories: Life Science News

3D Structure of A Nucleus and Chromosomes

Bio Imaging - 20 November 2017 - 8:28am
As lack of high-resolution tools for direct accesses, our understanding still remains controversial on the higher-order structure of human chromosomes between a few tens and hundreds of nanometers. In this work, the three-dimensional (3D) spatial structure of a human prophase nucleus and chromosomes was revealed by using a powerful 3D imaging tool, serial block-face scanning electron microscopy (SBFSEM).
Categories: Life Science News

A new map exhibit documents evolving views of Earth’s interior

Science News - 19 November 2017 - 1:00pm
"Beneath Our Feet" puts maps on display to show how people have envisioned and explored Earth’s subsurface.
Categories: Life Science News

Camera Technology: The Stacked Color Sensor

Bio Imaging - 18 November 2017 - 8:46am
Red-sensitive, blue-sensitive and green-sensitive color sensors stacked on top of each other instead of being lined up in a mosaic pattern – this principle could allow image sensors with unprecedented resolution and sensitivity to light to be created. However, so far, the reality hasn't quite met expectations. Researchers from Empa and ETH Zurich have now developed a sensor prototype that absorbs light almost optimally – and is also cheap to produce.
Categories: Life Science News

The Arecibo Observatory will remain open, NSF says

Science News - 17 November 2017 - 9:15pm
The iconic Arecibo radio telescope has survived Hurricane Maria and dodged deep funding cuts.
Categories: Life Science News

eDNA tool detects invasive clams before they become a nuisance

Life Science News - 17 November 2017 - 8:17pm
When seeking a cure for a disease, early detection is often the key. The same is true for eliminating invasive species. Identifying their presence in a lake before they are abundant is vital. A recent study successfully used environmental DNA to detect invasive clams in California and Nevada lakes. Researchers believe this tool can help identify pests before they become a problem.
Categories: Life Science News

Skeletons could provide clues to who wrote or protected the Dead Sea Scrolls

Science News - 17 November 2017 - 8:05pm
Skeletons suggest a group of celibate men inhabited Dead Sea Scrolls site.
Categories: Life Science News

The key to breaking down plastic may be in caterpillars’ guts

Science News - 17 November 2017 - 7:12pm
Caterpillars that feast on plastic have different gut microbes than those that eat a grain-based diet.
Categories: Life Science News

Age, gut bacteria contribute to MS disease progression, according to study

Life Science News - 17 November 2017 - 5:54pm
Gut bacteria at a young age can contribute to multiple sclerosis disease onset and progression, new research indicates.
Categories: Life Science News

Using eDNA to identify the breeding habitat of endangered species

Life Science News - 17 November 2017 - 4:37pm
Using wide-ranging eDNA analysis combined with traditional collection survey methods, researchers have identified the breeding site of critically endangered fish species Acheilognathus typus in the mainstream of Omono River in Akita Prefecture, Japan.
Categories: Life Science News

The future of cell culture: A new continuous bioprocess developed

Life Science News - 17 November 2017 - 4:37pm
A revolutionary technique to allow the continuous production and collection of cells has been developed by scientists.
Categories: Life Science News

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